link*:*https://personal-care.evonik.com/product/personal-care/en/products-solutions/concepts/pages/tattoo-care.aspx?valueId=20409&productId=31225&download=custpropfile. Page. Get FREE. However, they cannot integrate with the existing cement lipid in the extracellular matrix. Super long, so bear with me. Labmuffin has a good post on her blog about this as well, so look there if you want more detail. “They are both investment skin care products,” says Chung. I’ll give out your badge as soon as I’m back on desktop! They say: A face treatment formulated with a maximized concentration of lipids (2 per cent pure ceramides, 4 … Our high potency formulas are concentrated in pure actives and proven to absorb optimally into skin. Press question mark to learn the rest of the keyboard shortcuts. I do have some questions about the conclusions being drawn, hopefully you can help clear things up? The brand states that this product will help restore the natural skin barrier. Another thing that complicates it is that base components of moisturizers are different in every study, even though they controlled for the base without ceramide, the delivery mechanism would always be changed depending on the type of emulsion, presence of penetration enhancers etc. September 17, 2020. In some pathologic conditions like SLS-damage, there is increased hexagonal arrangement which translates to a damaged barrier. This anti-aging cream provides improved hydration in 24 hours. correct. Takes 10-12 weeks apparently and signs you up for L’Oréal emails but it’s freeeee, https://cloud.mail.skinceuticals.com/ACED?media=Social&product=TLR&fbclid=IwAR039zvC8mP9yswcgomao9OpOYUcBySSUWYihmpU3JtsNW9m-r6GSHVR8CU. The patent, from what I saw, gave no indication or evidence that it was helpful for TEWL. US Only. SkinCeuticals Triple Lipid Restore 2:4:2. Sale Sold out. Triple Lipid Restore. Triple Lipid Restore 2:4:2 has been clinically proven to improve the visible appearance of skin smoothness, laxity, pores, and overall radiance. *Some reddit-wide technical limitations apply, but we’re doing our best! Unit price / per . This "normal" state actually functions to allow some absorption from outside the epidermis and also to allow water to escape. It just sounds so unnecessary. dupes? Mon 10am - 8pm. Skinceuticals Retexturing Activator. Your skin naturally contains lipids like triglycerides, fatty acids, squalane, wax esters, and cholesterol. If that effect exists, does the amount of benefit increase proportionally to the amount of ceramides included, or does it increase at a different rate?. Its fast-absorbing formula has antioxidants, vitamins and other nutrients to fight free-radical damage and smooth skin texture, too. The research housed the lipids in a base of ethanol (alcohol) and propylene glycol. My skin has never been more moisturized, radiant and smooth. I have updated the instructions accordingly. Last one . SkinCeuticals. Dry/Sensitive | Mod | European | Patch test ALL the things! Fill in your contact information below to receive your complimentary sample. It may be that I am just unaware of the study that does. Get FREE. This luxurious anti-aging cream provides your skin with lipids, 2% pure ceramides, 4% natural cholesterol, and 2% fatty acids. It’s useful to note, at this concentration, the lipid mixture outperformed petrolatum by the 2-hour mark, which is impressive since petrolatum is often considered the gold standard in preventing transepidermal water loss. Skinceuticals C E Ferulic 1 Fluid Ounce - Anti-aging Vitamin C and E Serum Repairs and Protects Skin… CDN$179.99 (CDN$599.97 / 1 l) In Stock. What are ceramides, and why are they beneficial to skin? They may still work for you because lotions and creams are generally moisturizing, but the ceramides are likely adding nothing. Triple Lipid Restore 2:4:2 is an anti aging cream formulated with a maximized concentration of lipids: 2% pure ceramides, 4% natural cholesterol, and 2% fatty acids. Many of the other topics have been covered pretty extensively already - chemical exfoliants, vitamin c, retinoids, niacinamide, etc, and companies have already responded by being transparent about %'s, pH, etc. In short, probably. This is the best ratio of combining the three components in order to … This anti-aging cream provides improved hydration in 24 hours. Makes me feel normal. Skinceuticals Correct A.g.e. SkinCeuticals Ultra Facial Defense SPF 50+ 55.00 . Alternatively, find out what’s trending across all of Reddit on r/popular. u/the_acid_queen and u/BurgundySnail pointed out that it is hard to pinpoint what the source of the free fatty acids are in Sk-Influx from looking at the ingredient list, and u/the_acid_queen kindly pointed us to the document linked below, which despite not explaining the source of free fatty acids in the blend, nonetheless states in bullet three under "properties," that the product is a "a concentrated mix of different types of ceramides, cholesterol, free fatty acid and phytosphingosine". Do you know of any products that do? I could see your line of thinking. So... what is a good budget ceramide cream? It's one of the reasons why so many companies rely on SK-Influx - in addition to being very easy to just "drop in" to an existing formula, a la Drunk Elephant's reformulation of Lala, it's a relatively inexpensive way to put in a pinch of ceramides so you can market your product as such. This is sort of my way of sharing knowledge in the way it was shared with me so many years ago. As you age, your complexion creates less of certain lipids, resulting in a loss of facial fullness, an uneven texture and the appearance of fine lines and wrinkles. SkinCeuticals HA intensifier firming anti-wrinkle serum~1oz-New sealed. Regular price $155.00 Sale price $155.00 Regular price. I love Skinceuticals especially Triple Lipid Restore. Leave a Reply Cancel reply. SK-INFLUX ingredients: Ceramide 3 (Ceramide NP), Ceramide 6 II (Ceramide AP), Ceramide 1 (Ceramide EOP), Phytosphingosine, Cholesterol, Sodium Lauroyl Lactylate, Carbomer, Xanthan Gum. Skinceuticals Triple Lipid Restore. SkinCeuticals HA intensifier firming anti-wrinkle serum~1oz-New … The function of the ceramides-cholesterol-fatty acid substance is to integrate itself into the cement lipids so that it will pack tighter. 107 sold. No. “Triple Lipid Restore actually restores to your skin what it loses as we age. I remember in a youtube video for paulas' choice (skincare chat with bryan) they said that for Paula's Choice Ceramide-Enriched Firming Moisturizer they used the expensive ceramide instead of the usual cheap one. $69.27. LIMITED TIME OFFER. Triple Lipid Restore 2:4:2 is an anti aging cream formulated with a maximized concentration of lipids: 2% pure ceramides, 4% natural cholesterol, and 2% fatty acids. 42. Thank you! That process is not especially predictable (microflora on the skin seems to affect this as well, such as those suffering with malassezia overgrowth) and can vary between people. SkinCeuticals Triple Lipid Restore 2:4:2 - 1.6oz/48ml , New in Sealed Box. For a limited time, you can see if you qualify for a free sample to try it out for yourself! But Dermstore’s Digital Merchandising Director Jessica Chung—longtime La Mer user—was surprised to find SkinCeuticals Triple Lipid Restore with almost the same, if not better, results. The likeliest source of free fatty acids is the sodium lauroyl lactylate, which at acidic pH's, breaks down into lactic acid and lauric acid, the latter of which being a free fatty acid. Ethanol most definitely did not help with barrier repair, and the propylene glycol, despite some humectant properties, probably didn't help too much either. The product has 2% pure ceramides, 4% natural cholesterol, and 2% fatty acids. Their ad on Facebook says "get a free sample of Triple Lipid Restore" but the link says, "get a free sample of one of our customer favorite products." I don't have a blog - I just work day in and day out on skincare technologies. availability: In Stock; Add to Cart. I love posts like this! Do ceramides need to be combined with cholesterol and free fatty acids to work? This is the skinceuticals triple lipid restore 2:4:2 moisturizer and it retails for $128.00. https://www.youtube.com/watch?v=s4Fn6g178xQ&t=1592s, increasing skins firmness with it's really cool combination of a high amount of vitamin C retinol and of course the complex of ceramides we are using ceramides in this formula in an amount that I granted I'm not privy to the quantitative formulas from other brands that use products they're used ceramides in their products but I know what a lot of raw materials cosmetic ingredients cost, ceramides the type that we are using the blend we're using and the amount in which we are using them it's not cheap so the product is priced accordingly III but I get its it is a higher price point then most of I think all of our other facial moisturizers but I would put this moisturizer in terms of anti-aging results I would put it up against anything else out there including from the super high-end lines if you haven't tried it yet please do so if you're if you're curious and if individuals within your budget and if it isn't we have other products in our resist skin balancing skin recovery lines that are also brilliant formulations so as much as I would love for everyone to try this new moisturizer if it isn't within your skincare budget I don't want you to feel like you're missing out on something wonderful because you can get pretty darn close to the results from this product from other products in our range particularly if you wanted to weave in a booster or two which I know ultimate. Page. Thank you for being so generous with your time, but I think it would help many more of us If you could teach us about other misconceptions and marketing gimmicks in skincare (vs checking ingredients on someone’s favorite moisturizer). Your skin deserves safe, effective formulations. Thu 10am - 8pm. Hey Skincare Addicts—SkinCeuticals here! Did that research take into consideration the effect that other ingredients may have on ceramide penetration and efficacy? Does this mean that all the products containing SK-Influx on the market will damage your barrier? Skinceuticals . Press question mark to learn the rest of the keyboard shortcuts. LIMITED TIME OFFER. Triple Lipid Restore 2:4:2 has been clinically proven to improve the visible appearance of skin smoothness, laxity, pores, and overall radiance. I love this. SkinCeuticals AGE Interrupter Brand New, 1.7oz Authentic, Factory Sealed Box. There seems to be a lot of interest in ceramides and not a lot of transparency on the part of skincare companies, so I thought I’d make this post. Skinceuticals Triple Lipid Restore 2:4:2* key ingredients are 2% pure ceramides 1 and 3 which improve skin's barrier functions and increase hydration, 4% natural cholesterol to improve elasticity and finally, 2% fatty acids to restore overall lipids balance. $129.19. ADVERTISEMENT. Skinceuticals Triple Lipid Restore 2:4:2 is the latest innovation from Skinceuticals. Free shipping. The SkinCeuticals Triple Lipid Restore and the A.G.E. So, what is this miracle cream, and are there any good (affordable!) TL;DR there are no "budget" ceramide creams that reflect the research. The research by Mao-Qiang and Feingold shows that a total combined concentration of 1% to 1.6% of ceramides, cholesterol and free fatty acids is capable of repairing the barrier. To ensure the authenticity and best quality of your SkinCeuticals products, we carefully select our retailers. The secret to the Triple Lipid Restore formula is 2% ceramides, 4% natural cholesterol and 2% fatty acids. That is approximately 10x less than what researchers showed to be effective. This lipid loss compromises skin’s natural protective barrier, resulting in visible signs of accelerated aging, as skin loses its ability to effectively self-repair. However, it does mean that the dusting of ceramides in those products are mostly for marketing purposes and provide little to no functional benefit. Another important thing to note is the pH of products as enzymes that hydrolyses glucocerebrosidases to actual ceramides is optimal at 5.1-5.6 pH so if you keep applying moisturizers beyond this pH, those lamellar bodies would not integrate with the existing ones. Another one I want to see someone go in depth about is pH adjusting toners. This was my first reddit post so I felt compelled to answer as many questions as I could. The Skinceuticals Triple Lipid Restore 2:4:2 has brought some of those key ingredients together. Emulsion types are definitely one of the topics everyone should discuss as they affect delivery and activity of cosmeceuticals. With age, lipid production declines. Passionate about something niche? KAILO Wellness Medispa. This item: SkinCeuticals Triple Lipid Restore, 1.6 Fluid Ounce CDN$159.99 (CDN$94.11 / 1 fl oz) In Stock. The maximum recommended usage for SK-Influx is 15%, which would result in a .2% final ceramide content. Using the specific molar mass of cholesterol (386.65g/mol), an average molar mass of ceramides (700g/mol), and a typical molar mass of fatty acids commonly used in skincare, such as linoleic, linolenic and stearic acids (280g/mol), we can calculate the molar ratios of the lipids in SK-Influx. I think Multi Lamellar emulsion is actually a good way of delivering lamellar bodies where they are supposed to go. Triple Lipid Restore 2:4:2 is an anti aging cream formulated with a maximized concentration of lipids: 2% pure ceramides, 4% natural cholesterol, and 2% fatty acids. Rhonda's Staff Pick is SkinCeuticals Triple Lipid Restore. Wrinkles, discoloration, and sagging skin are a fact of life, but you can minimize them with the right routine. Anyway, thank you both it's so nice to know someone is also geeking out on these kinds of stuff. Ships from and sold by Canada Skin Solutions. It's optional to sign up for loreal emails! They sometimes, more vaguely, say that it has “2.5% active matter”, but they are adding .5% cholesterol and .5% phytosphingosine in addition to the 1.5% ceramides to get to that number. I got this sample and I'm in love. Complete your regimen with a SkinCeuticals mineral sunscreen. I don't remember the details though! Last one. A daytime vitamin c antioxidant face serum that delivers advanced environmental protection and diminishes the appearance of fine lines and discoloration By email, SMS or other social media). Please call 1.877.900.face (3223) to place your order. SkinCeuticals Discoloration Defense 30ML BRIGHTER-LOOKING SKIN - … Sign in using your Sampler account (or join, it’s free!) Because there have been so many questions about this, I want to emphasize - many of the products mentioned in this thread have worked very well for many people, and they should* continue to use the products that work for them*. Free shipping . Would love to learn more abt these marketing tricks. ‼ ️. Found dupes: The Ordinary Natural Moisturizing factors + HA // Kiehl’s Ultra Facial Cream . Find all the best-sellers like SkinCeuticals C E Ferulic, SkinCeuticals Triple Lipid Restore 2:4:2, SkinCeuticals HA Intensifier, SkinCeuticals Hydrating B5 and many more. Imagine this, the cer-cho-FA ratio is like a grout that you need to apply in between your tiles (corneocytes). Warm a small amount of Triple Lipid Restore 2:4:2 between the fingertips. With fewer lipids than skin on the face, the neck’s skin barrier can weaken as early as age 30. All the typical HGs on here seem to be out... Ceramides are very expensive to purchase from raw materials suppliers. I'm curious as to what you thoughts are on QV Intensive with Ceramides - Light Moisturising Cream? US Only. Serum 10 AOX+ (30ml) Ideal for sensitive skin types or conditions to help restore healthy looking skin, Serum 10 AOX+ neutralizes free radicals, defends against environ Read More. Cookies help us deliver our Services. Read More. That means at an optimal 3:1:1 molar ratio at a concentration of 1-1.2%, with any component being dominant, the ceramide concentration needs to be .3%-.7%. Perhaps, but I am not aware of research that clarifies this. Replenish your nutrients and bring your skin back to life with SkinCeuticals Triple Lipid Restore 2:4:2. Quantity: Decrease Quantity: Increase Quantity: items in stock Create New Wish List; Product Details . It's constantly in flux - at some periods it's stronger and has higher concentrations of lipids and less permeability, and at other times it's weaker and has less lipids and more permeability. There is research by Mao-Qiang and Feingold (they are experts on this topic and have a number of very good papers on this - google their names and “physiologic lipids” and you can even see some of their full papers as pdf’s) that indicates that when any one of these components is used in isolation of the others, or in the wrong molar ratios, it actually delays repair of the barrier. Simply calculating the ratio between the weights % of the components to calculate ratios is different from molar ratios, which factor in the molar mass of each material. Stratia Liquid Gold (especially concerning because the product is often marketed as having the ideal 3:1:1 ratio which SK-Influx is ridiculously far from; the test version on the founder’s blog originally used 10% SK-Influx, resulting in .15% ceramides, but the current ingredient list suggests they’re using it at a 1% concentration or less, meaning .015% ceramides or less). MSRP: Was: Now ... Write a Review × SkinCeuticals Triple Lipid Restore. ), which is good news, since most people in the general population looking for ceramide-laced products would fall into this category. Phyto Corrective Gel $ 80.00 A hydrating, soothing gel serum with botanical ingredients ideal to calm and hydrate skin while improving visual redness. James Street, 4006, Australia. Weight Loss, Fat Loss, Fitness . Reliable (props to them for telling you straight up it’s 3% SK-Influx, meaning it has .045% ceramides so still low but better). Email: … Taking that into consideration, I was thinking quantities less than 1-1.6% could be effective. Price: $ 105.00 CAD Quantity: Add to cart. Free Shipping on Orders $100+ FREE SHIPPING ON ORDERS $150+ 888-910-0623; S [email protected] Contact Us; My Cart 0 Item $0.00 . Skinceuticals . A best-seller with nearly 400 five-star reviews Multi lamellar emulsion is actually good. D probably love them just as much without the help of any the! And the nasties are kept out of occlusives like petrolatum sign in using your Sampler Account or! A return to baseline pre-acetone other nutrients to fight free-radical damage and smooth Dermstore.com this product can be... And 10 parts free fatty acids to work sort of fix the barrier is Increase Quantity: Add cart... List published with Allure is correct then it 's optional to sign up for loreal emails skin lipids improve. The benefit is delayed that the product has 2 % pure ceramides, 4 natural. 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